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PROJECTS OF 2004-06 BATCH of M.Sc (BIOTECHNOLOGY)
 

Sl. No.

Name

MSc Marks %

Title of Project

Name of Institutions

Name of the Guide

1

Anupama Mahato

65.8

Title : Studies on micropropagation of Nyctanthes arbortristis : Effect of Nutritional factor and plant Hormone Regime

RPRC Bhubaneswar

 

2

Arjun Ghosh

65.6

Title : Cloning of small Nuclear RNAs found in Giardia lamblia

Brief : Giardia lambia is an unicellular eukaryotic microorganism that commonly cause diarrhea disease. In this present study, two different rRNA strains of Giardia lambia has been cloned to study on the factors involved in the biogenesis of rRNA and to identify some novel pathway for future development of chemotherapeutic interventions and rational drug designing.

National Institute of Cholera and Enteric Diseases, Kolkata

Dr.Sandipan Ganguly, Senior Research Officer.

3

Arpita Sarkar

79.8

Title : Analysis of Genetic variation in Vinca sp by RAPD Technique

Sangene Biotech, Bangalore

 

4

Bandita Swain

60.0

Title : Antimicrobial activity of Bacteria

Brief : The present work has been carried out to find out suitable bacteria having antimicrobial activity against many microbes, exploiting the antagonistic behaviour of micro-organisms and was screened out some of the bacterial isolates having antimicrobial properties in wide spectrum, from a total of60 bacteria tested against Fusarium sp.

RPRC Nayapalli, Bhubaneswar

Dr.Nibha Gupta, Sr.Scientist, RPRC.

5

Barnalika Ojha

55.9

Title : In vitro rapid multiplication of Banana (Musa paradisiaca) through corm and cormlets)

KPRC, Bhubaneswar

 

6

Chanchal Roy

60.0

Title : Enhancement of lipid peroxidation and depletion of superoxide dismutase and catalase level in wiss Albino mice by Lead Acetate

Brief :  The presnt study is a clinical data review type. In this study animals subjected to lead acetate exposure to observe its effect on the behaviour of antioxidative enzyme and the lipid peroxidation level in the liver as liver is the site of drug metabolism and detoxification of the body. And observed that lipid peroxidation in case of lead treated was increased more than 2 fold in the liver tissue in comparision to normal control.

Chittaranjan National Cancer Institute, Kolkata

Dr.Sudin Bhattacharya, Senior Scientist Officer.

7

Chandna Dixit

67.9

Title : Irt 1 over expression in Brassica juncea Lcv varuna

Brief : Iron trafficking in the whole plant is necessary for essential physiological processes to work properly. To present investigation is to raise transgenic plant of Brassica overexpressing the iron transporter gene irtl. These transgenic plant should be able to transfer iron efficiently while growing in iron deficient soil.

JNU, ILS, New Delhi

Prof.(Dr)Baishnab C.Tripathy

8

Debikalyani Mohanty

60.25

Title : Evaluation of serum MDA and magnesium level in cerebrovascular Accident

Brief :  The study was carried out with an objective to assess the role of lipid peroxidation and magnesium status in cerebrovascular stroke and was concluded that increase in oxidative stress and hypomagnesemia are a potential risk factor for development of cerebrovascular artherosclerosis leading to stroke. It is possible that therapeutic substitution of magnesium and anti oxidant micronutrient may be beneficial for stroke treatment.

SCB Medical College, Cuttack

Dr.Prakash ch
Mohapatra, Professor,
HOD Biochemistry.

9

Devisha Sinha

71.2

Title : Analyzing the expression of a recombinant protein in cho cells at different temperature and also in different media

Brief :  CHO cell line is the first complete mammalian cell culture able to provide the cell need to produce recombinant protein under strictly defined serum and protein free culture condition. From  the present study it is concluded that viable cellcount is more in PF – CHO medium than SFM- CHO. The protein expression of CHO cellline is more in PF- CHO media and its expression in SFM is more precise.

In this study CHO cell line are cultured using PF & SF media and the viability of cells are observed.

Dr. Reddy’s laboratory, Hyderabad

Mr.K.B.Ravi Shankar,
Associate, Scientist.

10

Dipica Kerketta

60.6

Title : Effect of cultural condition on phosphate solubilization capacity of fungi

Brief : The importance of this study was to find out phosphate solubiliting fi=ungus. Phosphorus is the major nutritional requirements of crops but its supply is from nonrenewable energy source. In the present study, some fungi were tested to solubilize phosphorous from RP & TCP.

Regional Plant Research Centre, Bhubaneswar

Dr.Nibha Gupta, Sr.Scientist, RPRC.

11

Doyeli Chakraborty

64.0

Title : In plant training  on quality control of milk in dairy industry.

Brief :  The study reveals about the various industrial sterilization used for the quality control of dairy product

Mother Dairy Institute, Kolkata

 

12

Hemanta Kumar Sahoo

65.4

Title : Germplasm conservation of some potential medicinal plants of Satkosia wild life sanctuary through seed Gene Bank

Brief : The medicinal plants of forest region are presently facing constant threat of extinction owing to habital degradation, forest five and over exploitation of drug plants. Most of the plants are habitat specific and scientifically little understood.

The present study was carried out with an aim to document and to develop strategy and seed technology of endangered medicinal plant seeds for exsites conservation by choosing satkoria wildlife sanctuary in Orissa as a special habitat.

RPRC Bhubaneswar

Dr.R.C.Mishra, Scientist.

13

Ipsita Mohanty

58.8

Title : Microcosm study of V. cholerae 01/0139 and conversion of viable but non culturable (VBNC) to rough strain a new insight

Brief : The present study was undertaken with the aim to disclose the survival longevity of V.Cholerae in endemic area of cholera in Orissa by taking microcosm study to understand the conversion of VBNC to smooth stream taking Balb/c mouse as a model and to exhibit the status of virulent genes.

RMRC, Bhubaneswar

Dr.G.P.Chotray, Deputy
Director & Head of
Dept of Pathology &
Microbiology

14

Jatin ku Meher

62.3

Title : Analysis of Genetic variations in Ocimum Spp by RAPD Technique

Brief :  Standardization of protocols for isolation at genomic DNA from plant source was done and both quantitative estimation at DNA and to determine the natural distribution of genetic variation in the ocimum species by using RAAPD technique.

Sangene Biotech, Bangalore

Dr.P.C.Panda

15

Jeevan Dash

58.7

Title : Study of Genetic variation in philodendron of the family Araceae through chromosome and RAPD analysis

RPRC Bhubaneswar

 

16

Jyoti Kullu

69.0

Title : Studies on genetic relationship among the varieties / species of the genes polyscias, schefflera and calathea using RAPD markers

Brief :  The present investigation offers a optimization at primer screening for evaluation at genetic relationship at the varities/species of the genus polyscias and calathea through RAPD analysis.

RPRC Bhubaneswar

Dr.G.R.Rout, DSc, FNASc, Senior Scientist.

17

Kanchan Mala Bihari

64.

Title : Isolation and identification of Aeromonas species from different Hospitalised diarrhoea patients and water samples

SCB Medical College, Cuttack

 

18

Kumkum Das

70.9

Title : PCR based marker assisted selection for Bacterial Blight resistance genes in rice

Brief :  To study the polymorphism among the parents used in the breeding program to improve resistance to blast disease and to screen the selectual gene pyramided lines.

CRRI, Cuttack

Dr.J.N.Reddy, Senior Scientist.

19

Lipsa Rani Samal

63.6

Title : Isolation of Staphylococcus from the Hospital personnel environment and their Antibiogram with special Emphasis on Methicillin Resistance

SCB Medical College, Cuttack

 

20

Mahamaya Patra

68

Title : Screening techniques for Industrial Microbes

Brief :  In order to observe the enzymatic activity of industrially important microbes, a wide range of micro – organisms esp fungi are screened in different media under asceptic conditions.

RPRC, Bhubaneswar

Dr.Nibha Gupta, Sr.Scientist

21

Manasee Tripathy

67.4

Title : Biochemical Speciation of Microbacterium Isolates

AIIMS, New Delhi

 

22

Milirani Sahoo

59.0

Title : Serum calcium and magnesium levels in patients with essential Hypertension

Brief :  The study revealed that low serum ca2+ levels in hypertensive patients in comparision to the healthy indivisual and low serum mg2+ in hypertensive patients in comparision to healthy controls. High serum sodium in hypertensive patients in comparision to healthy controls and high serum potassium in hypertensive patients in comparison to healthy controls.

SCB Medical College, Cuttack

Dr.P.C.Mohapatra, Prof & HOD Biochemistry.

23

Monalisa Priyadarsini

64.2

Title : Immune Response to Surface Lipids in Human Filarial Infection

Brief :  The three groups of individuals endemic normal asymptomatic microfilariane carriers and chronic filariasis patients have generated a specific IgG and IgM response against the adult surfacelipid antigens. Immunolongitudinally using surface lipid antigens will be useful to assess the role of antibodies in controlling microfilamania in people living in the endemic regions.

RMRC, Bhubaneswar

Dr.M.K.Das, Deputy Director, Division of Immunology.

24

Mridusmita Bora

70.08

Title : Two Medical Plant Species Gomphostemma (A Medicinal Plant)

Brief :  Gomphostemma species was selected which is a medicinal herb and was propagated  through tissue culture using different hormonal concentrations and combinations with MS media. This was used for the mass propagation of Gomphostemma.

Deffence Research Development Organisation Tezpur, Assam

HKGogoi, Scientist, Head, Tissue Culture Division.

25

Paramita Das

60.5

Title : Effect of immunosuppressive agent on polymorpho Nuclear Neutrophil

Brief : To evaluate the role at chemotherapeutic agents in turns of Immunosuppression with special reference to polymorphonuclear neutrophil function.

Calcutta School of Tropical Medicine

Dr,Samaresh Chowdhury, Head, Dept of Biochemistry and Medical Biotechnology.

26

Parna Bhattacharya

73.6

Title : Anti Leishmanial Activity of Arabinosylated Lipoarabinomannan an Alternative Therapeutic approach to Leishmaniasis

Brief : An unusual rate of glycolipid on the leishmaniasis & the role of Ara – LAM in the regulation  of impaired free radical generation during leishmaniasis & upregulation at TH1 cytokine and down regulation of TH2cytokine by Ara – LAM  during infection.

BOSE Institute, Kolkata

Dr.Subrata Majumdar, Reader, Dept of Microbiology.

27

Pramod Kumar Ranjit

56.7

Title : Study of Lipid profiles in Type-II Diabetes Mellitus

Brief : To evaluate the lipid profiles in type II diabetes mellitus, which is an indivisual risk factor for coronary heart disease.

SCB Medical College, Cuttack

Prof.Prakash ch Mohapatra, Professor & HOD Biochemistry.

28

Pramod Kumar Sahoo

61.5

Title : Effects of different Hormones on in Vitro propagation of Musa Clone AAA cv. Robusta

RPRC, Nayapalli, Bhubaneswar

 

29

Pratima Basak

73.4

Title : Prolonged effect of immunosuppressive agents on Macrophage mediated phagocytosis

Brief : The aim of the present work is to evaluate the role of chemotherapeutic agents in terms of immunosuppression with special reference to macrophage agents an animal system, to delineate the CMI status in the subject concerned , to characterize the role of specific immuno cell under the event.

School of Tropical Medicine Kolkata

Dr.Samaresh Choudhuri, Professor & Head, Dept of Biochemistry & Medical Biotechnology.

30

Purbaja Bhattacharyya

60.4

Title: Effects of Growth Hormones on in vitro micropropagation  of musa clone ABB CV Banta

RPRC Nayapalli, Bhubaneswar

 

31

Rajib Lochan Satpathy

52.0

Title : Analysis of Genetic diversity of the Genes crotalaria linn (Leguminosae : papilionoideae) through molecular markers

Brief :  The present study involves 8 species of crotalaria was taken up and the genetic diversity of the species were analysed through molecular markers like RAPD & ISSR which can be achieved by isolation & purification of genomic DNA, studying genetic variation in crotalaria, evaluation of genetic relationship among different species of crotalaria to find out the degree of correlation among different species taken for present investigation & to construct a phenomenon gram from RAPD and ISSR data.

RPRC, Bhubaneswar

Dr.Pratap Chandra Panda, Sr.Scientist, Taxonomy & Conservation Division.

32

Rashmi Karan

60.3

Title : Microbiological & chemical estimation of milk & milk products

Brief : The present study deals with the microbiological and chemical analysis of water, milk and milk product in industry.

Vaishal, Patliputra, Dugdh, Uppadak Sahkari Sangh, Patna

 

33

Reena Parida

62.7

Title : Characterization  of Bacteria with Reference to morphophysiological and phosphate solubilisation properties

Brief : Phosphate solubilizing bacteria are efficiently used to solubilize phosphate which is present in insoluble form in soil. So PSB are used in the present study tosolubilize phosphate present in TCP and RP.

RPRC, Bhubaneswar

Dr.Nibha Gupta, Sr.Scientist, RPRC.

34

Rosen Khan

54.5

Title : Physiological Basis of rooting ability in Hunteria zeylanica and Gerbera manghas two rare and endangered tree species

Brief : The study deals with the estimation of photosynthetic pigment, carbohydrate, protein, polyphenols & analysis of rooting induced enzymes viz – polyphenoloxidase & peroxidase with special reference to the stock plants of Hunteria Zeylanica & Cerbera manghas of family Apocyanaceae as a part of forest biotechnology pertaining to evaluation of rooting ability of priority/selected reforestation sps.macropropagation.

RPRC, Bhubaneswar

Dr.U.C.Basak, Scientist

35

Sabyasachi Prusty

58.9

Title : The phenotypical and Biochemical effects of growth regulators on in vitro  propagation of musa clone AAA Cv. Grand Naine

Brief : An attempt was made to develop an clonal propagation system in Musa accuminata CV. Grand Naine by manipulating the growth regulators. In this investigation it is detected that the intensity of morphogenesis is dependent on growth regulatrs. Though BAP alone can help shoot regeneration & growth. The presence of adenine and JAA promoted high frequency shoot regeneration & growth. Similarly, for root generation Auxin is supplied along with cytokinin & adenine for better rooting of plantlets. Rapid clonal propagation system helps for field plantation specially for commercial purposes.

RPRC, Bhubaneswar

Dr.Bandita Deo, Scientist, Banana Tissue culture lab.

36

Sachin Gupta

60.5

Title : Quality control and analysis of Milk and Milk products Himalayan Milk products union limited Siliguri, West Bengal

Himalayan Milk Product Union Limited (HIMUL), Matigara, Darjeeling

 

37

Sameer Kumar Barik

55.9

Title : Cloning and molecular characterisation of GFP Gene and its products

Brief : The main objective of this study is to carry out cloing and molecular characterization of GFP gene and the purification of the recombinant proteins by the process of affinity chromatography.

RPRC Bhubaneswar

Dr.Jeevan kumar Ramineni, Geno Bioscience Pvt. Ltd.

38

Sandip Das

51.3

Title : Survey and isolation of Bioctive compounds from flora of West Bengal and observation of their Antibacterial spectrum

CICFRI, Kolkata

 

39

Sarmila Sahoo

57.7

Title : Biochemical and molecular characterization of enteropathogenic Escherichia coli” isolated from Diarrhoea patients Hospital based study

Brief :  The main objective of this study are – isolation of E – coli from diarrhea patients following standard bacteriologic technique, identification by biochemical tests, molecular characterization by PCR study, confirmation by the above isolates of E.Coli by specific antisera to test antibiotic sensitivity of the organism against some selected antibiotics.

RMRC Bhubaneswar

Dr.B.B.Pal, Senior Research Officer.

40

Sasmita Pradhan

64.0

Title : Over expression of por C in Brassica juncea L CV varuna

Brief : The porc gene was transformed to Brassica funcea cul varuna through plant tissue culture method to develop porc overexpression transgenic Brassica plants. Here 643 explants were infected with agrobacterium containing porc(s) in their T-DNA. Out of 643 explants, 8 transgenic plants were confirmed by PCR amplification by taking G – DNA as template & 35s forward & porc reverse as primers. Inthis experiment, 92 explants were infected with only PCAMBIA vector as control which gives no regeneration in shoot induction medium. These 8 porc over expression transgenic Brassica plants may be easily withstand oxidation stress induced by high light.

JNU, Institute of Life Sc, New Delhi

Prof.B.C.Tripathy, Supervisor, School of Life Sciences.

41

Satyadev Bose

59.08

Title : Analysis of Genetic variations of two piper SP’s by RAPD technique

Brief : The study attempts to understand the level of variations in two species of the piper belonging to the family piperaceae, using RAPD markers. In RAPD analysis, the amplification product having the banding pattern more than 7 in the studied species of piper, where the marker ranges from 1131 to 450 bp.

Sangene, Bangalore

Dr.A.K.Mukherji.

42

Saurav mishra

63.5

Title : Isolation purification, extraction and metabolic profiling of Batalain pigments from Amaranthus tricolor

Brief : Anthocyanins represent a class of important antioxidants. The present study deals with the correlation between antioxidant capacity of anthocyanins and their  chemical structure.

IIT Kharagpur

Dr.Satya Hari Dey, HOD, Dept of Biotechnology.

43

Siva Narayan Nayak

54.5

Title : Serum Malondialdehyde, Zinc and Magnesium levels in Brochial Asthma

Brief : The study was taken to estimate serum malonylaldehyde,zinc and magnesium level in bronchial asthma cases and to correlate them with disease process.

SCB Medical College, Cuttack

Dr.P.C.Mohapatra, Professor & HOD, Dept of Biochemistry.

44

Smruti Ranjan Dash

58.08

Title : Effect of Antitubercular  therapy on liver function status in patients of pulmonary tuberculosis

Brief : The study is aimed to evaluate the liver function status in patients with active pulmonary tuberculosis receiving antituberculosis treatment and to assess the role different risk factors in anti TB drugs – induced hepatitis that is to elucidate the relationship between age, sex, alcohol intake, nutritional status and disease extent with Drug induced hepatotoxicity.

SCB Medical College, Cuttack. 

Dr.P.C.Mohapatra, Professor & HOD, Dept of Biochemistry.

45

Soujatya Dhar

60.8

Title : Study of Human leucocytes in vitro and mouse Bone marrow in Vivo for Assaying Genotoxicity

Brief : The objective of the study is to study the human leukocyte in vitro and study of mouse bone marrow chromosomes in vivo. The present study deals with the effects of inorganic lead nitrate administered orally in mics, to study the mitotic index in bone marrow chromosomes preparations in vivo.

Vivekananda Institute of Medical Science, Kolkata

Geeta Talukdar, MD PhD, Sr. Scientist, Dept of Pathology.

46

Subhashish Jena

56.7

Title : A dissertation of micro propagation of Vanilla planifolia

Brief : Invanilla the regeneration potency is high in stipulated period and the chances of failure is reported which ultimately results in yield ofbetter plantlets. The mortality is feeble in primary & secondary hardening which infers the plantlet as much beneficial in tissue culture.

Sarat Biotech, Bhubaneswar

Ms.Usha Kiran, Managing Director

47

Subhashree Suchismita Nayak

61.0

Title : Assessment of lipid profile and lipid peroxidation in patients of rheumatoid Arthritis

Brief : The study was performed on 20 diagonised cases of rheumatoid arthritis and comprised of estimation of serum MDA and lipid profile in the above groups with an objective to evaluate the lipid peraxidation status and dyslipidemia associated rheumatoid arthritis patients.

SCB Medical College, Cuttack

Dr.Rachita Nanda, Lecturer, Dept of Biochemistry.

48

Sukanta Palui

60.8

Title : Effects of Immunosupressive agents on cytotoxic T-cells functions

Brief :  Cytotoxic T-lymphocytes(CTL) have the capacity to kill the target cell by cytolytic function. Different immunosuppressive agents have immunosuppressive effects on immunocytes including T- Lymphocytes. The present study was carried out by using two chemotherapeutic drugs such as bleamycin & cyclophosphamide & their effect on cytotoxic T – lymphocytes, was studied.

School of Tropical Medicine Kolkata

 Dr.Samaresh Choudhuri, Professor & Head, Dept of Biochemistry & Medical Biotechnology

49

Sumana Chatterjee

71.9

Title : Biotechnological methods in the study of Anaemia

Brief : The research project was carried out to diagnose the haemoglobinopathies, detection of their mutations and the carrier status in the population of varying degree of age, sex etc. Both phenotypic & genotypic interactions were studied.

Vivekananda Institute of Medical Science, Kolkata

Geet Talukdar, MD PhD, Sr.Scientist, Dept of Pathology.

50

Sumanta chatterjee

72.3

Title : Prolonged effect of Immunosuppressive agents on CD4 T-cell as mediated through S-RBC Rosetting

Brief : The aim of the present work is to evaluate the role of chemotherapeutic agents in terms of immunosuppression with special reference to CD – 4 T-cell function carrying objectives like to observe generalized effects of chemotherapeutic agents on animal system, to delineate the CMI status in the subject concerned to characterize the role of specific Immune cell(CD – 4 T Cell)under the event.

School of Tropical Medicines Kolkata

Dr.Samaresh Choudhuri, Professor & Head, Dept of Biochemistry & Medical Biotechnology.

51

Suvakshan Dutta

62.5

Title : Study of expression and purification of an entamoeba protein in bacterial  expression system

Brief : The present study was carried out by purifying the entamoeba protein with an aim to gather knowledge about the structural and functional aspects of this bacterial protein that will act as a model for probable drug target or vaccine candidate.

IIT, Kharagpur

Dr.Sudip K.Ghosh, Assistant Professor, Dept of Biotechnology.

52

Swarna Prava Samal

66.3

Title : Standardization of protocol for in vitro propagation of Bamboo (Bambusa Nutans)

KPRC(Kalinga Plant Research Centre)

 

53

Sweta Das

69.5

Title : Sequence of deletion clones of fibroin Gene of Antheraea mylitta

Brief : Sequentially deleted and circularized Antheraea mylitta fibroin CDNA(~7.5kb) cloned in pBluescript vector using Exonuclease III/mung beer nuclease, containing varying length of insert CDNA was transformed into XL Blue E.coli cell. The recombinant clones were selected on LB – ampicillin plates. After cloning different length of the deleted clones of the A.mylitta fibroin CDNA was determined by digesting the clones with ECORI and analysed on agarose gel. The deleted clones having various lengths of CDNA inserts were grouped & selected according to their size & sequence.

Indian Institute of Technology, Kharagpur

Ananta kumar Ghosh, Professor, Dept of Biotechnology.

54

Truptimayee Behera

68.2

Title : PCR based marker assisted selection for Bacterial Blight resistance gene in rice

Brief : Parental analysis of swarna, IR 64 and resistance gene pyramid line IRBB 60 (carrying Xa-4,Xa-5,Xa-13 & Xa-21) was performed. Sequence tagged site (STS) markers RG 556,RG136 and Xa21 for Xa-5.Xa-13 & Xa – 21 respectively were used for PCR analysis. PCR amplified products showed distinct polymorphism between both bacterial blight resistance gene pyramid line, IRBB 60 & susceptible swarna and IR – 64.

CRRI, Cuttack

J.N.Reddy, Senior Scientist, Molecular & Plant pathology research lab.

55

Uma Kundu

63.5

Title : Evaluation of Serum IgE, T3, T4 and Tsh with the help of ELISA

Brief : The use of ELISA technique in estimation of total IgE levels and T3, T4 and TSH levels of different patients, sothat this can be utilized regularly in laboratories.

Immunomedicare and Research Institute, Kolkata

Dr.Prosanta Roy Karmakar, Director.